|
1) Physiologic changes in the concentration of Antibodies to SS-A/Ro and SS-B/La
2) Pathologic changes in the concentration Antibodies to SS-A/Ro and SS-B/La
Systemic Lupus Erythomatodes,
Progressive Systemic Sclerosis,
Sjögren’s Syndrome
Rheumatoid Srthritis
anti-SS-A (Ro)
Reference values
dependent on method |
Immunofluorescence method. |
negative |
ELISA |
|
|
Units |
negative |
< 8 |
U/ml |
equivocal |
8 – 10 |
U/ml |
positive |
> 10 |
U/ml |
anti-SS-B (La)
Reference values
dependent on method |
Immunofluorescence method. |
negative |
ELISA |
|
|
Units |
negative |
< 3 |
U/ml |
equivocal |
3 – 4 |
U/ml |
positive |
> 4 |
U/ml |
|
Anti – SS-A/Ro
-
Systemic Lupus Erythomatodes 30 – 50 % patients
- Primary Sjögren’s syndrome 60 –70% patients
-
Secundary Sjögren’s syndrome up to 95 % patients
Anti – SS-B/La
- Systemic Lupus Erythomatodes 15 % patient
-
Primary Sjögren’s syndrome 45 –60% patients
-
Secundary Sjögren’s syndrome up to 87 % patients
|
(ANCA)
