Thrombocytes contain most of the blood serotonin and great amounts of histamine, adrenaline and lysosomic enzymes. Secreting vasoactive substances both actively and passively under the influence of various irritants, thrombocytes are important for tonicity and permeability of the vessel wall.
The formation of the hemostatic plug (cellular stage of hemostasis, i.e., the initial stage in hemostasis) is completely independent on the coagulation in the narrower sense. The cellular stage can be divided into:
- adhesion of thrombocytes,
- secretion of active substances, and
- aggregation of thrombocytes.
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