Plasma Cell

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FUNCTION OF THE PLASMA CELL

DEVELOPMENTAL FORMS OF PLASMA CELL
Introduction
Centrocyte
Centroblast
Immunoblast
Plasmablast
Proplasmocyte
Plasma Cell
 

PLASMA CELL

 

Description:

Plasma cell is fully mature B-lymphocyte. It is round or oval.
Binuclear and multinuclear plasma cells can be seen in blood smears.
They usually are located around the blood capillaries. Plasma cells secrete the majority of immunoglobulins.

Size:

12-15 µm.

Cytoplasm:

Typically intensely blue or ultramarine in color, with a clearer area adjacent to the nucleus. The Golgi complex is particularly well-developed. The cytoplasm has a coarse endoplasmic reticulum filling a greater part of cell except the perinuclear halo.
The cytoplasm can contain microvacuoles and has a reddish color because of the presence of immunoglobulin in the endoplasmatic reticulum.         

Nucleus:

Eccentrically laid and small in relation to the size of the cytoplasm; generally a clear perinuclear halo can be seen. The chromatin is often clumped towards the margin of the nucleus in a so-called cartwheel fashion.

Nucleoli:

Not visible.