The earliest recognizable cell of the erythrocytic series. It is a large oval or round cell.
Size:
15 -20 µm
Cytoplasm:
Dark blue with a pale perinuclear halo. Immature proerythroblast does not have hemoglobin in the cytoplasm. The synthesis of hemoglobin begins round the nucleus. The cytoplasm is stained gray-blue.
Nucleus:
Relatively large, with a network of chromatin strands. After the synthesis of hemoglobin begins, the chromatin of the nucleus becomes clumped.
